Apr 24, 2020
College. Senior Year. A cancer diagnosis.
Before graduation, a crash course: Cancer 101.
The student and patient, Addison, quizzes her doctor, Jason Luke, on the life-saving thesis he drafted on using immunotherapy as part of her cancer treatment.
College, senior year, a cancer diagnosis. Before graduation, a crash course, Cancer 101. Student and patient, Addison, quizzes her doctor, Jason Luke, on the lifesaving thesis he drafted on using immunotherapy as part of her cancer treatment.
What did it feel like to be diagnosed with melanoma when you were
21? It's kind of funny, I didn't really know what melanoma was. And
I told my mom. And her reaction was probably more significant than
me hearing it myself. And she found within the day the best
melanoma specialists in the area on his day off. And I was seeing
him by that afternoon.
And so you went forward and had standard treatment with surgery and
they took out a lymph node. How did that all go, and what did you
think about that as you're going through?
Melanoma doesn't feel like anything, it's your skin. You feel the
surgery, you feel side effects from treatments. Immunotherapy is a
whirlwind because there is no standard set of side effects.
And so you have to prepare for everything, which almost makes you
just prepare for nothing, because you don't know what's going to
happen. That was my senior year of college. I was really focused on
my education and finishing school on time. I don't remember feeling
like it was any sort of life threatening or life changing event at
that time.
It wasn't until way later that I felt that way. My boyfriend,
Nathan, and I, we were on our second day making dinner at his
house. He's outside getting the grill ready. And my tongue starts
fluttering. I'm chopping up something in the kitchen. And I'm like,
how embarrassing if he comes in and I can't talk to him?
So I head to his bathroom to just wait it out. And I had a seizure
in his bathroom. So he came in and found me seizing. He called
9-1-1, and the ambulance took me to the nearest hospital. They
found a tumor the size of a walnut in an area of my brain that
controlled my speech.
I immediately talked to a neurosurgeon about getting it out as soon
as possible. That's when I was like, OK this is for real, this is
scary.
So how did you process that?
My roommate at the time came with me for the results that showed
the brain tumor. So it's me and my 24-year-old girlfriend sitting
in there. And we walked out, and we went and got ice cream, because
ice cream helps everything.
Do you remember what your interactions were like with your parents?
How did they talk to you, what did they say?
My parents were surprisingly calm on the phone. And we set a date.
There was a little hope left in me that it wasn't cancerous. And
then after brain surgery, I remember waking up in the bed and
asking if it was melanoma. And my parents nodded their heads. And
that was a hard moment because I knew I was in for a long haul.
That's when you came in.
I've always been somebody who just moved 100 miles an hour all the
time. I've stopped for a second to think like, oh my god, what
would it be like to have your child have to go through something
like this? It's very hard to think about.
How did you decide who your best doctors were going to be?
I think finding the right doctor is crucial. You came in to one of
our appointments. And you're younger than a lot of the doctors that
I had seen. And you talk very quickly. You're clearly incredibly
smart and up on your research. And we all admired your hair,
because you have some flow.
Well, I glad to know that these are elements of decision
making.
You told my parents and me that you had been thinking about the
treatment plan over the weekend. And you were 100% certain to go
with this plan. And it was that trust we had in you that is so
important. And you made that decision that ultimately is credited
for saving my life.
You're in the field of researching melanoma, which has a huge
strides right now and huge advancements. And it's probably one of
the most exciting cancers, because you are curing cases. Do you
think immunotherapy is going to be the answer ultimately?
Well, I think as we're learning more about immune system treatments
for cancer, it's become apparent that what we had missed previously
is a reason that other treatments worked because of the immune
system. And so to that extent, I would say, yes, absolutely,
immunotherapy is going to become an important part of most cancer
treatments.
But I also have to frankly say that our ability to truly understand
what's going on is honestly quite neophyte. And so there's a lot
more to do there.
When I received my remission diagnosis, you were on paternity
leave. I've always wondered, do you feel like you missed out on
telling me about remission?
The answer is definitely yes. It really is meaningful to be able to
be there in that moment and deliver news like that. I think about
my role as an oncologist, it's really to help support people as
they go through their journey and provide them with the best
information and care that I can. You only have to see a case like
yours once. And you'll keep doing it every day just in hopes that
you could see it again.
Addison graduated, she's now a CPA. Dr. Luke, Conquer Cancer Grant
recipient, continues to explore immunotherapy research. To ensure
researchers like Dr. Luke keep uncovering new and better cancer
treatments, donate to Conquer Cancer today. Visit
conquer.org/donate.